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Our..analysis..is,..however,..limited..by..the..absence..of..data..on..expression..of..novel..molecular..prognostic..markers..of..AML..such..as..nucleophosmin-1..(NPM1)..mutation,..or..allelic..burden..of..FMS-related..tyrosine..kinase-3..(FLT-3)..internal..tandem..duplication..mutation..and..CCAAT/enhancer..binding..protein-&#x003B1;..(CEBPA),..among..others.40,..41,..42,..43,..44,..45..This..limitation..is..inherent..to..retrospective..registry..studies…This..could..be..explained..in..part..by..a..significantly..higher..use..of..ATG..in..the..FB2..group..(79%..vs..33%,..P<0.0001)…All….Rights….Reserved…..Blood..2005;..106:..2854&#x02013;2861.ArticlePubMedISICASSpiekermann..K,..Bagrintseva..K,..Schoch..C,..Haferlach..T,..Hiddemann..W,..Schnittger..S…Reduced..mortality..after..allogeneic..hematopoietic-cell..transplantation…BU…12.8&thinsp;mg/kg…(FB4)…in…patients…with…AML…and…myelodysplasia…at…various…stages…of…the…disease…showed…no…difference…in…2-year…OS…whether…ivBUCY,…FB2…or…FB4…was…used…(50%…vs…47%…vs…49%,…P=NS).17…Unfortunately,…only…a…small…percentage…of…allografted…recipients…in…that…study…were…in…first…CR…(CR1)…(ivBUCY…(n=6,13%),…FB2…(n=15,…37%)…and…FB4…(n=6,…24%)),…not…allowing…a…solid…conclusion…to…be…drawn…about…the…impact…of…BU…dose…intensity…among…RIC…regimens…in…this…particular…setting.17Accordingly,…we…performed…a…comparative…analysis…of…two…commonly…used…RIC…regimens,…namely…FB2…(fludarabine…plus…i.v….Haploidentical…or…cord…blood…allograft…recipients…were…excluded.Statistical…analysisPatient-,…disease-…and…transplant-related…variables…of…the…two…groups…were…compared…using…chi-square…or…Fisher&#x02019;s…exact…test…for…categorical…variables…and…Mann&#x02013;Whitney…test…for…continuous…variables.Probabilities…of…LFS…and…OS…were…calculated…using…the…Kaplan&#x02013;Meier…estimate….Biol…Blood…Marrow…Transplant…2002;…8:…145&#x02013;154.ArticlePubMedISICASKashyap…A,…Wingard…J,…Cagnoni…P,…Roy…J,…Tarantolo…S,…Hu…W…et…al….

Severe..hypoalbuminemia..at..day..90..predicts..worse..nonrelapse..mortality..and..overall..survival..after..allogeneic..hematopoietic..stem..cell..transplantation..for..acute..myelogenous..leukemia..and..myelodysplastic..syndrome…Related….39.NataljaAndreeva-Sezondikojohoty.2010.FB2….[Magnet….Link]……..File….Size….:….461.99….KB……..File….Count….:….1……..Create….Time….:….2015-09-27….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….461.99….KB….11.NataljaAndreeva-Devjatdnejdovesny.2010.FB2….[Magnet….Link]……..File….Size….:….491.38….KB……..File….Count….:….1……..Create….Time….:….2015-11-06….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….491.38….KB….22.NataljaAndreeva-Metel.2010.FB2….[Magnet….Link]……..File….Size….:….812.08….KB……..File….Count….:….1……..Create….Time….:….2015-11-07….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….812.08….KB….29.NataljaAndreeva-Ognennajalilija.2010.FB2….[Magnet….Link]……..File….Size….:….852.00….KB……..File….Count….:….1……..Create….Time….:….2015-11-06….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….852.00….KB….52.NataljaAndreeva-JAsadovnikomrodilsja.2010.FB2….[Magnet….Link]……..File….Size….:….568.89….KB……..File….Count….:….1……..Create….Time….:….2015-08-11….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….568.89….KB….53.NataljaAndreeva-JAstanutoboj.2010.FB2….[Magnet….Link]……..File….Size….:….842.37….KB……..File….Count….:….1……..Create….Time….:….2015-11-06….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….842.37….KB….9.NataljaAndreeva-GrobnicaNapoleona.2010.FB2….[Magnet….Link]……..File….Size….:….502.55….KB……..File….Count….:….1……..Create….Time….:….2015-08-16….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….502.55….KB….1.NataljaAndreeva-512kilobajtdollarov.2010.FB2….[Magnet….Link]……..File….Size….:….750.95….KB……..File….Count….:….1……..Create….Time….:….2015-11-07….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….750.95….KB….23.NataljaAndreeva-Muzhzaalibi.2010.FB2….[Magnet….Link]……..File….Size….:….497.22….KB……..File….Count….:….1……..Create….Time….:….2015-11-07….51.NataljaAndreeva-JErastrelca.2010.FB2.fb2….497.22….KB………Blood…2001;…98:…3569&#x02013;3574.ArticlePubMedISICASAoudjhane…M,…Labopin…M,…Gorin…NC,…Shimoni…A,…Ruutu…T,…Kolb…HJ…et…al….Simultaneous..detection..of..NPM1..and..FLT3-ITD..mutations..by..capillary..electrophoresis..in..acute..myeloid..leukemia…In..recipients..50..years..of..age,..FB2..resulted..in..better..2-year..LFS..(634%..vs..427%,..P=0.02)..and..OS..(684%..vs..457%,..P=0.006);..a..lower..2-year..non-relapse..mortality,..albeit..not..statistically..significant..(153%..vs..296%,..P=0.06),..was..observed..with..FB2…Moreover,…the…2-year…cumulative…incidence…of…chronic…GVHD…(any…grade)…was…similar…between…patients…conditioned…with…FB2…or…FB4…(P=0.51)….Download..Link..[Magnet..Link]..[Torrent]..High..speed..Download..kps…..Leukemia….2013;….27:….2068&#x02013;2072.ArticlePubMedKako….S,….Morita….S,….Sakamaki….H,….Ogawa….H,….Fukuda….T,….Takahashi….S….et….al…..

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